Keiichiro Nishida Selected Research

Cytokines

3/2022	Pre-treatment plasma cytokine levels as potential predictors of short-term remission of depression.
2/2022	CD30-targeted therapy induces apoptosis of inflammatory cytokine-stimulated synovial fibroblasts and ameliorates collagen antibody-induced arthritis in mice.
4/2020	Induction of CEMIP in Chondrocytes by Inflammatory Cytokines: Underlying Mechanisms and Potential Involvement in Osteoarthritis.
10/2019	Mechanical strain attenuates cytokine-induced ADAMTS9 expression via transient receptor potential vanilloid type 1.
5/2015	Tocilizumab, a humanized anti-IL-6R antibody, as an emerging therapeutic option for rheumatoid arthritis: molecular and cellular mechanistic insights.
1/2014	SH3BP2 gain-of-function mutation exacerbates inflammation and bone loss in a murine collagen-induced arthritis model.

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Keiichiro Nishida Research Topics

Disease

41	Rheumatoid Arthritis 10/2022 - 01/2004
9	Inflammation (Inflammations) 02/2022 - 10/2004
9	Pain (Aches) 01/2022 - 06/2010
9	Osteoarthritis 03/2021 - 10/2007
8	Arthritis (Polyarthritis) 02/2022 - 02/2003
5	Major Depressive Disorder (Major Depressive Disorders) 10/2022 - 01/2017
4	Surgical Wound Infection 02/2022 - 11/2011
4	Neoplasms (Cancer) 01/2010 - 01/2002
4	Chondrosarcoma 05/2005 - 01/2002
3	Infections 02/2022 - 11/2011
3	Congenital Abnormalities (Deformity) 01/2022 - 12/2016
3	Schizophrenia (Dementia Praecox) 01/2016 - 01/2013
3	Venous Thrombosis (Deep-Vein Thrombosis) 06/2010 - 01/2002
2	Necrosis 03/2022 - 05/2015
2	Diabetes Mellitus 02/2022 - 04/2007
2	Sleep Initiation and Maintenance Disorders (Insomnia) 09/2021 - 01/2019
2	Sleepiness 05/2020 - 01/2017
2	Hypertrophy 01/2019 - 01/2009
2	Disease Progression 11/2018 - 06/2017
2	Wounds and Injuries (Trauma) 08/2015 - 01/2004
2	Synovitis 01/2015 - 01/2002
1	Chronic Obstructive Pulmonary Disease (COPD) 02/2022
1	Chronic Pain 09/2021
1	Hypoxia (Hypoxemia) 01/2021
1	Nutrition Disorders (Nutritional Disorders) 01/2021
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2021
1	Edema (Dropsy) 05/2020
1	Dizziness (Lightheadedness) 05/2020
1	Neuralgia (Stump Neuralgia) 05/2020
1	Weight Gain 05/2020

Drug/Important Bio-Agent (IBA)

7	Biological ProductsIBA 02/2022 - 11/2011
7	Antirheumatic Agents (DMARD)IBA 02/2022 - 11/2011
6	CytokinesIBA 03/2022 - 01/2014
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2018 - 05/2005
4	Pharmaceutical PreparationsIBA 03/2022 - 01/2013
4	CollagenIBA 02/2022 - 04/2002
3	TeaIBA 10/2022 - 01/2014
3	EnzymesIBA 03/2022 - 07/2004
3	Interleukin-6 (Interleukin 6)IBA 03/2022 - 05/2018
3	4-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA 09/2021 - 05/2017
3	LigandsIBA 01/2021 - 03/2017
3	AutoantibodiesIBA 03/2015 - 02/2003
2	Mirtazapine (Rexer)FDA LinkGeneric 10/2022 - 01/2017
2	Certolizumab Pegol FDA Link 07/2022 - 01/2017
2	Antidepressive Agents (Antidepressants)IBA 03/2022 - 01/2017
2	MicroRNAs (MicroRNA)IBA 03/2022 - 01/2021
2	ImmunosorbentsIBA 03/2022 - 04/2011
2	InterleukinsIBA 03/2022 - 05/2015
2	Lymphotoxin-alpha (Lymphotoxin)IBA 01/2021 - 06/2018
2	C-Reactive ProteinIBA 01/2021 - 04/2007
2	Hyaluronic Acid (Hyaluronan)IBA 04/2020 - 12/2018
2	Abatacept (Orencia)FDA Link 01/2020 - 05/2014
2	A-factor (Streptomyces)IBA 06/2017 - 05/2017
2	Aluminum Oxide (Sapphire)IBA 02/2017 - 01/2014
2	Paliperidone Palmitate FDA Link 01/2016 - 01/2016
2	Risperidone (Risperdal Consta)FDA LinkGeneric 01/2016 - 01/2016
2	Monoclonal AntibodiesIBA 05/2015 - 02/2003
2	Etanercept (Enbrel)FDA Link 08/2012 - 12/2010
2	Collagen Type II (Type II Collagen)IBA 06/2011 - 02/2003
2	Histone Deacetylases (Histone Deacetylase)IBA 01/2010 - 10/2004
2	Aggrecans (Aggrecan)IBA 01/2009 - 05/2005
2	Interleukin-1beta (Interleukin 1 beta)IBA 05/2008 - 05/2005
2	fibrin fragment D (D-dimer)IBA 01/2008 - 01/2002
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2006 - 01/2002
2	Angiogenesis Inducing Agents (Angiogenesis Factor)IBA 04/2002 - 01/2002
1	Interleukin-2 (IL2)IBA 03/2022
1	Interleukin-8 (Interleukin 8)IBA 03/2022
1	Interleukin-4 (Interleukin 4)IBA 03/2022
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 03/2022
1	Therapeutic UsesIBA 02/2022
1	Brentuximab VedotinIBA 02/2022
1	Biosimilar PharmaceuticalsIBA 01/2022
1	Tacrolimus (Prograf)FDA LinkGeneric 01/2021
1	mirogabalinIBA 05/2020
1	Pregabalin (Lyrica)FDA Link 05/2020
1	Calcium Channels (Calcium Channel)IBA 05/2020
1	Metalloproteases (Metalloproteinases)IBA 10/2019
1	ThrombospondinsIBA 10/2019
1	Matrix Metalloproteinases (MMPs)IBA 10/2019
1	DisintegrinsIBA 10/2019
1	Proteins (Proteins, Gene)FDA Link 01/2019
1	Insulin-Like Growth Factor I (IGF-1)IBA 01/2019
1	Collagen Type XIBA 01/2019
1	tofacitinibIBA 11/2018

Therapy/Procedure

8	Arthroplasty 10/2022 - 01/2002
8	Orthopedic Procedures 02/2022 - 12/2010
5	Therapeutics 02/2022 - 01/2002
4	Aftercare (After-Treatment) 08/2018 - 12/2010
3	Replacement Arthroplasty 01/2022 - 06/2016
3	Knee Replacement Arthroplasty (Total Knee Replacement) 03/2021 - 01/2002
3	Elbow Prosthesis 02/2017 - 01/2014
2	Transcranial Direct Current Stimulation 07/2022 - 01/2019
2	Operative Surgical Procedures 01/2022 - 11/2011
2	Osteotomy 12/2019 - 12/2016
2	Drug Therapy (Chemotherapy) 06/2017 - 03/2017
2	Arthrodesis 01/2016 - 01/2004
1	Operative Time 02/2022
1	Exercise Therapy (Therapy, Exercise) 01/2022
1	Activities of Daily Living (ADL) 09/2021
1	Punctures 01/2021